Step 5 of 9 · Core Curriculum
Active vs Chronic Lesions
A required learning step before pattern recognition. Classify each finding as active, chronic, or mixed — and explain the visual evidence.
Learner prompt
“Is this lesion potentially reversible, chronic/scarring, or mixed?”
Active
- Hypercellularity
- Necrosis
- Cellular crescents
- Endocapillary proliferation
- Active interstitial inflammation
- Tubulitis
- Edema
- Thrombosis
- Vasculitis
Chronic
- Global or segmental sclerosis
- Fibrous crescents
- GBM thickening or duplication
- Interstitial fibrosis
- Tubular atrophy
- Vascular medial thickening
- Intimal fibrosis
- Arteriolar hyalinosis
Mixed
- Fibrocellular crescents
- Active inflammation superimposed on chronic scarring
- Chronic lesions with active injury
Assessment items
- Classify lesion as active, chronic, or mixed.
- Explain the visual evidence.
- Link active/chronic classification to clinical reasoning and prognosis.